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Powders exert a drying (evaporative) effect. Lipophilic ointment (oil ointment) consists of a lipophilic base (paraffin oil, petroleum jelly, wool fat [lanolin]) and may contain up to 10 % powder materials, such as zinc oxide, titanium oxide, starch, or a mixture of these. Emulsifying ointments are made of paraffins and an emulsifying wax, and are miscible with water.
A given sustance does not necessarily behave as an agonist or antagonist at all receptor subtypes, but may act as an agonist at one subtype and as a partial agonist/ antagonist or as a pure antagonist (p. 214) at another. The abuse potential is also determined by kinetic properties, because development of dependence is favored by rapid build-up of brain concentrations. |
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