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Its congener, dihydroergotamine, is furthermore employed in orthostatic complaints. Other lysergic acid derivatives are the 5-HT antagonist methysergide, the dopamine agonists bromocriptine, pergolide, and cabergolide, and the hallucinogen lysergic acid diethylamide (LSD).
Certain prostaglandins or analogues of them (F2?: dinoprost; E2: dinoprostone, misoprostol, sulprostone) are capable of inducing rhythmic uterine contractions and cervical relaxation at any time. They are mostly employed as abortifacients (oral or vaginal application of misoprostol in combination with mifepristone).

 

Mucolytics, such as acetylcysteine, split disulfide bonds in mucus, hence reduce its viscosity and promote clearing of bronchial mucus. Other expectorants (e. g. , hot beverages, potassium iodide, and ipecac) stimulate production of watery mucus. Acetylcysteine is indicated in cystic fibrosis patients and inhaled as an aerosol.
Specific damage to bacteria is particularly practicable when a substance interferes with a metabolic process that occurs in bacterial but not in host cells. Clearly this applies to inhibitors of cell wall synthesis, because human and animal cells lack a cell wall. The points of attack of antibacterial agents are schematically illustrated in a grossly simplified bacterial cell, as depicted in.

 

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