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Consequently, the molecular weight of dextran circulating in blood will tend towards a higher mean molecular weight with the passage of time. The most important adverse effect results from the antigenicity of dextrans, which may lead to an anaphylactic reaction. Hydroxyethyl starch (hetastarch) is produced from starch.
During electrical excitation of the cell membrane of heart or smooth muscle, different ionic currents are activated, including an inward Ca2+ current. The term Ca2+ antagonist is applied to drugs that inhibit the influx of Ca2+ ions without affecting inward Na+ or outward K+ currents to a significant degree. Other labels are Ca-entry blocker or Ca-channel blocker. |
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