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The drugs principally used are thiazides (possibly combined with K+-sparing diuretics) and loop diuretics. Prophylaxis of renal failure. In circulatory failure (shock), e. g. , secondary to massive hemorrhage, renal production of urine may cease (anuria). By means of diuretics an attempt is made to maintain urinary flow. Use of either osmotic or loop diuretics is indicated.
In simplistic terms, activation of the sympathetic division can be considered a means by which the body achieves a state of maximal work capacity as required in fight or flight situations. In both cases, there is a need for vigorous activity of skeletal musculature.

 

Furthermore, psychic experiences may also activate the emetic center. The mechanisms underlying motion sickness (kinetosis, sea sickness) and vomiting during pregnancy are still unclear. Polar substances cannot reach the emetic center itself because it is protected by the blood-brain barrier.
In addition, a carrier (antiporter), utilizing the transmembrane Na+ gradient as energy source, transports Ca2+ out of the cell in exchange for Na+ moving down its transmembrane gradient (Na+/Ca2+ exchange).

 

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