Drug Name Ortho Tri-Cyclen

Therefore, receptor binding must not be implied until it can be shown that binding is saturable (saturability); the only substances bound are those possessing the same pharmacological mechanism of action (specificity); binding affinity of different substances is correlated with their pharmacological potency.
Site of action: mainly the proximal tubules. Mode of action: Since NaCl and H2O are reabsorbed together in the proximal tubules, Na+ concentration in the tubular fluid does not change despite the extensive reabsorption of Na+ and H2O.

 

Due to the reduced FSH stimulation of tertiary follicles, maturation of follicles and, hence, ovulation are prevented. In effect, the regulatory brain centers are deceived, as it were, by the elevated estrogen blood level, which signals normal follicular growth and a decreased requirement for FSH stimulation.
This requirement necessitates regular drug intake and a dosage schedule that ensures that the plasma concentration neither falls below the therapeutically effective range nor exceeds the minimal toxic concentration.