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(However, in pharmacological experiments on isolated cardiac muscle preparations a clear negative inotropic effect is demonstrable.) They are thus regarded as vasoselective Ca2+ antagonists. Because of the dilatation of resistance vessels, blood pressure falls. Cardiac afterload is diminished and, therefore, also oxygen demand. Spasms of coronary arteries are prevented.
Pantoprazole (Protonix) is in a class of drugs called proton pump inhibitors (PPI) which block the production of acid by the stomach. Other drugs in the same class include Lansoprazole (Prevacid), Omeprazole (Prilosec) and Rabeprazole (Aciphex). Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease and Zollinger-Ellison syndrome that are caused by stomach acid. |
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