Drug Name Alesse

In the colon, semifluid material entering from the small bowel is thickened by absorption of water and salts (from about 1000 to 150 mL/d). If, due to the action of an irritant purgative, the colon empties prematurely, an enteral loss of NaCl, KCl and water will be incurred.
In order to maintain body temperature at its physiological level, excess heat must be dissipated—the patients have a hot skin and are sweating. The hypothalamic temperature controller (B1) can be inactivated by neuroleptics (p. 236), without impairment of other centers. Thus, it is possible to lower a patient’s body temperature without activating counter-regulatory mechanisms.

 

The site and mechanism of action of barbiturates, antihistamines, and chloral hydrate are incompletely understood. All hypnotics shorten the time spent in the REM stages (B). With repeated ingestion of a hypnotic on several successive days, the proportion of time spent in REM vs. non-REM sleep returns to normal despite continued drug intake.
A particular adverse effect results from interference with gonadal hormones, as evidenced by the development of gynecomastia (enlargement of male breast). Clinical uses include conditions of increased aldosterone secretion, e. g. , liver cirrhosis with ascites.