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Treatment. Caloric restriction to restore body weight to normal is associated with an increase in insulin receptor number or cellular responsiveness. The releasable amount of insulin is again adequate to maintain a normal metabolic rate. Therapy of first choice is weight reduction, not administration of drugs!
Vegetable fibers in the diet act in this manner. They consist of the indigestible plant cell walls containing homoglycans that are resistant to digestive enzymes, e. g. , cellulose (1 4?-linked glucose molecules vs. 1 4? glucoside bond in starch, p. 153). Bran, a grain milling waste product, and linseed (flaxseed) are both rich in cellulose.

 

Demulcent lozenges containing surface anesthetics such as ethylaminobenzoate (benzocaine) or tetracaine may provide relief; however, the risk of allergic reactions should be borne in mind. Cough.
Endothelial impairment and hence dysfunction has been proven to result from smoking, and nicotine is under discussion as a factor favoring the progression of arteriosclerosis. By releasing epinephrine, it elevates plasma levels of glucose and free fatty acids in the absence of an immediate physiological need for these energy-rich metabolites.

 

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