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Thus, stimuli other than the original antigen(s) can act as triggers (A); e. g. , breathing of cold air is an important trigger in exercise-induced asthma. Cyclooxygenase inhibitors (p. 196) exemplify drugs acting as asthma triggers. Management. Avoidance of asthma triggers is an important prophylactic measure, though not always feasible.
The defecation reflex is triggered when the sigmoid colon and rectum are filled. A natural defecation empties the large bowel up to and including the descending colon. The interval between natural stool evacuations depends on the speed with which these colon segments are refilled. A large bowel irritant purgative clears out the entire colon.

 

If feasible, this approach is preferred because all pharmacotherapeutic measures entail significant adverse effects. Migraine is a syndrome characterized by recurrent attacks of intense headache and nausea that occur at irregular intervals and last for several hours.
Adrenal medulla. On the one hand, release of epinephrine elicits cardiovascular effects, such as increases in heart rate und peripheral vascular resistance. On the other, it evokes metabolic responses, such as glycogenolysis and lipolysis, that generate energy-rich substrates. The sensation of hunger is suppressed.

 

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