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Colospa is used for relief of abdominal pain, cramps, bloating and wind, diarrhoea or constipation associated with irritable bowel syndrome. It may also be used for other conditions as determined by your doctor.
Adverse effects: Because of verapamil’s effects on the sinus node, a drop in blood pressure fails to evoke a reflex tachycardia. Heart rate hardly changes; bradycardia may even develop. AV-block and myocardial insufficiency can occur. Patients frequently complain of constipation. Gallopamil (= methoxyverapamil) is closely related to verapamil in both structure and biological activity.

 

In general, an ODT is formulated as a bioequivalent line extension of an existing oral dosage form. Under this circumstance, it is assumed that the absorption of a drug molecule from the ODT occurs in the postgastric GIT segments, similar to the conventional oral dosage form. But this scenario may not always be the case.
Therapeutic measures. First attempts of a causal treatment consist of zanamavir, an inhibitor of viral neuraminidase, an enzyme necessary for virus adsorption and infection of cells. However, since symptoms of common cold abate spontaneously, there is no compelling need to use drugs. Conventional remedies are intended for symptomatic relief.

 

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