Drug Name Atarax

Osmotic laxative effects are also produced by the polyhydric alcohols, mannitol and sorbitol, which unlike glucose cannot be transported through the intestinal mucosa, as well as by the nonhydrolyzable disaccharide, lactulose. Fermentation of lactulose by colon bacteria results in acidification of bowel contents and microfloral damage.
Prednisone is a glucocorticoid prodrug that is converted by 11beta-hydroxysteroid dehydrogenase in the liver into the active form, prednisolone.[1] It is used to treat certain inflammatory diseases (such as moderate allergic reactions) and (at higher doses) some types of cancer, but has many significant adverse effects.

 

The drug does not cross the blood-brain barrier. Adverse effects. Cardiovascular crises are a possible risk: emotional stress of the patient may cause sympathoadrenal activation with epinephrine release.
The dose range encompassing the dose-frequency relationship reflects the variation in individual sensitivity to the drug. Although similar in shape, a dose-frequency relationship has, thus, a different meaning than does a dose-effect relationship. The latter can be evaluated in one individual and results from an intraindividual dependency of the effect on drug concentration.