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Norvasc (Amlodipine) belongs to a group of drugs called calcium channel blockers. Norvasc relaxes (widens) blood vessels and improves blood flow. Norvasc is used to treat high blood pressure (hypertension) or chest pain (angina) and other conditions caused by coronary artery disease. This medication is for use in adults and children who are at least 6 years old.
At this site, molecular oxygen is used in oxidative reactions. Because these enzymes can catalyze either hydroxylation or oxidative cleavage of -N-C- or -O-Cbonds, they are referred to as “mixedfunction” oxidases or hydroxylases. The essential component of this enzyme system is cytochrome P450, which in its oxidized state binds drug substrates (RH).

 

Indroduction of a small alkyl residue at the carbon atom adjacent to the amino group (ephedrine, methamphetamine) confers resistance to degradation by MAO (p. 80), as does replacement on the amino groups of the methyl residue with larger substituents (e. g. , ethyl in etilefrine).
This regulatory system consists of the CNS (brain plus spinal cord) and two separate pathways for two-way communication with peripheral organs, viz. , the somatic and the autonomic nervous systems.

 

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